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NCAA bracket predictions: Model shares surprising March Madness 2025 tournament picks​on March 17, 2025 at 11:51 pm

SportsLine’s model nailed 13 of the teams in the Sweet 16 last season and simulated the 2025 NCAA Tournament bracket 10,000 times

​SportsLine’s model nailed 13 of the teams in the Sweet 16 last season and simulated the 2025 NCAA Tournament bracket 10,000 times   

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The 2025 NCAA Tournament bracket features several players who can lead their team to a national title. Duke’s Cooper Flagg is averaging 18.9 points and 7.5 assists per game this season, and he’s knocking down 48.8% of his field goals. Flagg, who is expected to return following an ankle injury in the ACC Tournament, will lead the No. 1 seed Blue Devils against 2025 March Madness contenders in the East Region of the 2025 March Madness bracket, including Alabama, Wisconsin, Arizona and Oregon. Alabama’s Mark Sears is averaging 18.7 points per game, while Arizona’s Caleb Love scores 16.6 points per contest.

Will Duke reach the Final Four behind Flagg’s brilliance, or will Sears lead Alabama to its first national title? Which players have the chance to leave their mark on the NCAA bracket 2025? Before making any 2025 March Madness bracket predictions, be sure to check out the 2025 NCAA Tournament bracket picks from the proven computer model at SportsLine.

Their proven projection model has simulated every game in the tournament 10,000 times. It has absolutely crushed its March Madness picks recently, beating over 91 percent of all CBS Sports brackets in four of the past six tournaments. It was all over UConn’s championship run a year ago and nailed 13 teams in the Sweet 16. It also nailed Alabama’s Cinderella run to the Final Four as a 4-seed.

It knows how to spot an upset as well. The same model has produced brackets that have nailed 24 first-round upsets by double-digit seeds since its inception in 2016. There’s simply no reason to rely on luck when there’s proven technology to help you dominate your 2025 March Madness bracket picks. 

Now, with the 2025 NCAA bracket revealed, the model is simulating the matchups and its results are in. You can only see it over at SportsLine.

Three 2025 March Madness bracket games to watch

One of the most intriguing 2025 March Madness matchups to watch: No. 5 Michigan vs. No. 12 UC San Diego in the South region. The Wolverines will enter the 2025 March Madness bracket full of confidence after knocking off Wisconsin in the Big Ten Tournament title game. Guard Tre Donaldson has been the catalyst for Michigan’s success this season. The junior is knocking down 44.5% of his field goals while averaging 11.6 points per game. UC San Diego, meanwhile, is one of the most disruptive defensive teams in the nation. The Tritons are giving up only 61.6 points per game, which ranks sixth in college basketball.

Another 2025 NCAA Tournament matchup to keep an eye on is No. 8 Louisville vs. No. 9 Creighton in the South Region. Louisville is led by Chucky Hepburn, who was an all-ACC first team selection after averaging 16.2 points per game. The Cardinals are a well-balanced team with five players averaging at least 12.0 points per game. Creighton is led by Ryan Kalkbrenner, who joined Patrick Ewing as the only other player to win the Big East Defensive Player of the Year four times. Kalkbrenner is also effective on the offensive end of the floor, scoring 19.4 points per game. He ranks fourth in the nation in field goal percentage (65.5%).

Another 2025 March Madness game to watch out for: No. 4 seed Texas A&M will battle No. 13 seed Yale in the South Region. The Aggies are the top offensive rebounding team in the nation, averaging 16.19 offensive rebounds per game. Texas A&M posted an 11-7 record in SEC play and secured several impressive non-conference wins this season, beating the likes of Purdue, Texas Tech and Creighton. Yale, meanwhile, features one of the nation’s most explosive offenses. The Bulldogs are averaging 81.4 points per game, which ranks 23rd in college basketball. Yale beat Auburn in the first round of the NCAA Tournament last year, making this a game to circle when locking in your March Madness bracket picks. You can see the model’s 2025 NCAA bracket picks here.

How to make 2025 NCAA bracket predictions

Who wins every tournament-defining matchup? And which teams will make surprising runs through the 2025 NCAA Tournament bracket? With the model’s track record of calling bracket-busting upsets, you’ll want to see which stunners it’s calling this year before locking in any 2025 NCAA bracket picks.

So what’s the optimal NCAA Tournament 2025 bracket? And which NCAA Tournament Cinderella teams will shock college basketball? Visit SportsLine now to see which double-digit seeds you can back with confidence, all from the model that called UConn’s national title and nailed 13 Sweet 16 teams in 2024.

 

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